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Urban Science
A recent special by the Nature publishing group talks about the topic Cities and Science. A very interesting set of articles that explores the effect of the urbanization of the world population, in...
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Barcelona Biomedical Genomics Lab on Twitter
During our last retreat we decided to open a twitter account. Some of us (@nlbigas, @chris_zen, @elbioc) are already using twitter, but we found useful to have one group account where we can tweet and...
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Sample Level Enrichment Analysis (SLEA) in Gitools to assess the...
From an expression profile of a set of tumor samples, in Gitools you can perform SLEA to assess the transcriptional status of modules (ie. pathways) per sample. The identification of molecular...
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Insights into 14-3-3σ-mediated NF-κB role in breast cancer
14-3-3σ is an adaptor protein that regulates multiple signal transduction pathways. It has been described as a tumour suppressor in breast cancer, where it is often lost or repressed. Anna Bigas and...
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Alba is a PhD!
Last Monday, April 29th, Alba defended her PhD thesis at the PRBB. It was the highest point of a story that started some five years ago, when she joined our group to do her Master’s thesis. From...
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Mutual exclusion statistics and data events in Gitools
We’re pleased to announce another incremental release of Gitools, version 2.2. Amongst the many improvements (listed at the bottom of this post) we’d like to highlight the effort that we put into...
View ArticleOur paper on reduced mutation rate in exons due to differential mismatch...
We are happy to announce that our paper on reduced mutation burden in exons caused by differential mismatch repair has been published yesterday, 6th November in Nature Genetics. Reduced mutation rate...
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Introducing the Cancer Genome Interpreter
This is a post written by Abel, Carlota, David and Nuria for BioMed Central blog network Cancer Genome Interpreter (CGI) is an open platform designed to support the identification of tumor alterations...
View ArticleOur paper on how nucleosomes influence mutation rate leading to a 10bp...
We are very excited to share that our work describing the somatic and germline 10bp periodicity in the mutation rate within nucleosome-bound DNA was published in the last 1st of November Cell issue....
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